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This is possibly due to the absorption pattern of cyclobenzaprine, meaning that extended release cyclobenzaprine capsules may pose particular risks to the elderly ( 14). Some patients also report gastrointestinal issues (stomach problems) like nausea, vomiting, constipation, and loss of appetite, as well as dry mouth ( 11, 12).Ĭyclobenzaprine carries greater risks for elderly patients ( 13). The primary adverse side effects of cyclobenzaprine are related to the central nervous system (CNS), and include drowsiness, dizziness, and nervousness ( 10). Patients who suffer from fibromyalgia may find that cyclobenzaprine both relaxes their aching muscles and helps improve their sleep ( 8). Cyclobenzaprine is effective for relieving lower back and neck pain ( 6, 7). ![]() It can be used on occasion for chronic pain, though it’s less suited for this kind of pain ( 5). By preventing serotonin transmission, cyclobenzaprine alleviates pain by reducing the number of pain signals that reach the central nervous system.Ĭyclobenzaprine is most useful for cases of acute musculoskeletal pain and muscle spasms. Serotonin is a neurotransmitter chemical that helps carry pain signals to the brain ( 4). ![]() It works by inhibiting serotonin transmission at the spinal cord ( 3). Cyclobenzaprine relaxes muscles by reducing muscle spasms.Ĭyclobenzaprine shares chemical similarities to tricyclic antidepressants, which are also sometimes prescribed to address muscle pain ( 2). Other brands of cyclobenzaprine include Fexmid, FusePaq Tabradol, and Amrix (an extended-release capsule). ![]() Flexeril is the brand name for a muscle relaxant called cyclobenzaprine ( 1).
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